
Early releases for May 1, 2011 (about CUAJ early releases)
Isolated renal hydatid disease in a non-endemic country: a single centre experience
Alaa A. Mokhtar, MD; Ahmed Al Sayyah, MD; Hindi Al-Hindi, MD; Raouf M. Seyam, MD;± Waleed Al Khudair
Abstract
Study comparing the applicability of dorsal lumbotomy in older children
Jonathan Cloutier, MD; Nadim Haidar, MD; Marie-Pier Rompre-Deschenes, MD; Maryse Grimard, Stéphane Bolduc, MD, FRCSC
Abstract
A smoking cessation program as a resource for bladder cancer patients
Daniel Vilensky, MD; Nathan Lawrentschuk, MB BS, PhD, FRACS; Karen Hersey, RN;
Neil E. Fleshner, MD, FRCSC
Abstract
“Just what the doctor ordered”: Factors associated with oncology patients’ decision to bank sperm
Samantha Yee, MSW; Esme Fuller-Thomson, PhD; Catherine Dwyer, RN; Ellen Greenblatt, MD, FRCSC; Heather Shapiro, MD, FRCSC
Abstract
Undergraduate exposure to urology: impact of the distributed model of medical education in British Columbia
Nathan A. Hoag, MD; Reza Hamidizadeh, MD; Andrew E. MacNeily, MD, FRCSC
Abstract
Salvage radiotherapy after high-intensity focused ultrasound treatment for localized prostate cancer: feasibility, tolerance and efficacy
Thomas Ripert, MD; Younes Bayoud, MD; Rabah Messaoudi, MD; Johann Ménard, MD; Marie-Dominique
Azémar, MD; François Duval, MD; Tan Dat Nguyen, MD; Frédéric Staerman, MD
Abstract
Isolated renal hydatid disease in a non-endemic country: a single centre experience
Abstract
Objective: Isolated renal hydatid disease (HD) is rare in nonendemic countries. Clinical and radiological suspicion warrants appropriate serological tests, preoperative treatment and intra-operative precautions. We present a tertiary care centre experience of isolated renal HD in a non-endemic country.
Methods: We reviewed the medical records of patients with HD treated in the past 20 years. We identified patients with the definitive diagnosis of isolated renal HD and described their management.
Results: Of the 119 cases with HD, 6 were found to have isolated renal involvement (5%). Their median age was 46.5 (28-70) years. Five patients presented with flank pain and 1 had an incidentally discovered renal mass. Radiologic investigations raised the suspicion of possible HD in 4 cases, while 2 cases were diagnosed as renal tumours. Computerized tomography showed complex renal cyst in 4, solid renal mass with heterogonous enhancement in 2 and calcification in 5. Eosinophilia and indirect hemagglutination test (IHA) were positive in 3 of the 4 suspected cases. Three cases
were treated as renal tumours, while 3 were managed as HD. Four cases had total nephrectomy and 2 had partial nephrectomy. Histopathology revealed that all cases had renal HD. Patients were followed for a median of 7.3 (0.4-11.3) years with no evidence
of recurrence.
Conclusions: Isolated renal HD is a challenging preoperative diagnosis in non-endemic countries. The definitive diagnosis is only possible by histopathology. Retrospectively, HD mimicked renal tumours in half the cases and should be considered in the differential
diagnosis of renal space occupying lesions.
Study comparing the applicability of dorsal lumbotomy in older children
Abstract
Objective: Dismembered pyeloplasty through dorsal lumbotomy
to correct ureteropelvic junction obstruction is mainly successfully
performed in children under 5 years old for technical reasons.
We compared children who underwent dorsal lumbotomy by age
group (<5 vs. =5 years old) to determine if the surgical success and
long-term results were comparable.
Methods: We retrospectively reviewed the charts of 134 children undergoing a pyeloplasty. Group 1 consisted of children <5 years old (n = 90) and Group 2 consisted of children ≥5 years old. Patients’ characteristics, as well as hospital stay, narcotic use, radiologic follow-up and success rate, were compared. Success was defined by absence of symptoms and ≥50% reduction in renal pelvis anteroposterior diameter and/or scintigraphic normalization of the drainage T1/2 when obtained. Univariate analysis was performed to compare the groups.
Results: Mean age (years) and weight (kg) at surgery for Groups 1 and 2 were 1/8 kg and 11/35 kg, respectively. Mean operative time was 98 minutes versus 120 minutes, respectively; mean hospital stay was 2.5 days for both groups and analgesia requirement was 50% higher in Group 2. A Pippi-Salle stent was used in 90%
(n = 120) of cases. Mean follow-up was 26 months and the success rate was 89% and 90% for Groups 1 and 2, respectively.
Conclusion: Our study showed comparable success rates. We can
infer that, as a technique, dismembered pyeloplasty is effective and
safe in the younger and older children.
A smoking cessation program as a resource for bladder cancer patients
Abstract
Introduction: Continued tobacco use following a bladder cancer (CaB) diagnosis puts patients at risk for other tobacco-associated diseases and has also been associated with heightened risks of treatment-related complications, tumour recurrence, morbidity and mortality. Our aim was to determine if patients with CaB who continue to smoke warrant a smoking cessation program as a resource for improving their prognosis and long-term health.
Methods: A cross-sectional quantitative questionnaire-based study was performed between January and April 2009. We surveyed patients with a pathologically confirmed diagnosis of CaB during their cystoscopy appointments at a single cancer centre.
Results: One hundred patients completed the survey with 72% of them admitting to smoking in their lifetime. A third of respondents smoked at the time of their diagnosis; 76% of patients who had been active smokers at the time of their diagnosis (n = 33) reported smoking at some point thereafter and 58% continued to smoke. Among continued smokers, they were classified in the following categories: 26% were in precontemplation,” 5% in “contemplation,” 16% in “preparation,” and 53% in “action;” 37% of patients who continued to smoke were interested in a hospital-based smoking cessation program. Overall, 70% reported smoking as a risk factor for a poor CaB prognosis. The two most common barriers to quitting were “trouble managing stress and mood” and “fear of gaining weight.”
Conclusions: Based on the data from our centre, patients with CaB who continue to smoke after their diagnosis warrant a smoking cessation program as a resource for improving prognosis and long-term health. Further research should focus on establishing an efficacious and cost-effective program that provides these patients with the resources they need to quit smoking.
“Just what the doctor ordered”: Factors associated with oncology patients’ decision to bank sperm
Abstract
Introduction: The purpose of this cross-sectional study was to explore factors associated with oncology patients’ decision to bank sperm prior to cancer treatment.
Methods: Patients who were referred to the oncology sperm banking program between January 2009 and March 2010
were invited to complete an 18-item questionnaire during one of their sperm banking visits.
Results: Of the 157 cancer patients referred to the Mount Sinai Oncology Sperm and Tissue Bank for sperm banking during the 15-month period, 79 questionnaires were returned (50% response rate). Of the respondents, 89% were informed about sperm banking by their physician. Future family planning was cited as the main reason to bank. Cost was not a barrier for the vast majority of respondents. Forty percent of respondents banked sperm within 4 days prior to initiating cancer treatment. Most respondents relied on their physician for verbal information on sperm banking. Eightyone percent were unaware of any patient organizations that have educational materials on oncology fertility preservation.
Conclusion: Sperm banking prior to cancer treatment is the only proven method of preserving fertility for cancer patients. The two main determinants associated with deciding whether to bank sperm were: the physician’s recommendation and the patient’s desire for future fatherhood. Physicians play a key role in influencing patients’ decisions. The recommendation to bank sperm is a persuasive message if patients are clearly informed about their potential risk of infertility post-cancer treatment, and that sperm banking is an effective way of preserving fertility. Providing patients with education materials might enhance compliance in sperm banking.
Undergraduate exposure to urology: impact of the distributed model of medical education in British Columbia
Abstract
Objective: With the increased development of distributed sites for medical education across Canada, it is imperative we ensure that the quality of education is comparable between the different campuses. Our objective was to assess medical student experience and comfort with common urologic clinical encounters and to determine whether any differences exist between the distributed education sites at the University of British Columbia (UBC).
Methods: Questionnaires assessing urologic education were delivered simultaneously to all final-year UBC medical students attending campuses in Vancouver, Victoria and Prince George. Results were analyzed using descriptive statistics.
Results: Overall, 55.8% of students felt their exposure to urology was adequate in the medical curriculum; learners in the Northern Program (Prince George) ranked their clinical and didactic experiences significantly higher. Areas requiring improvement include teaching of the male genitourinary exam, digital rectal exam and sexual history, in which learners rated teaching “good/outstanding” in only 18.2%, 47.7% and 43.2% of cases, respectively. Overall, students were most comfortable with the following clinical encounters: urinary tract infection, nephrolithiasis, benign prostatic hyperplasia, hematuria, incontinence and prostate cancer. Few differences in student experience or comfort were noted related to campus site, gender or urology clerkship exposure.
Conclusion: A significant minority of learners perceived that they had inadequate exposure to urology in the undergraduate curriculum. Experience in urology was comparable across the distributed sites and was congruent with teaching objectives. Students were comfortable with the clinical scenarios deemed most important in the literature. Learners in the Northern Program were significantly more satisfied with their urologic teaching, which potentially highlights the advantages of learning in a smaller academic setting.
Salvage radiotherapy after high-intensity focused ultrasound treatment for localized prostate cancer: feasibility, tolerance and efficacy
Abstract
Background: The objective of this study is to evaluate the feasibility, tolerance and efficacy of salvage external beam radiotherapy (EBRT) in persistent or recurrent prostate cancer after failed high intensity focused ultrasound (HIFU) therapy.
Methods: We reviewed data on tolerance and oncologic outcomes for all patients with biopsy-proven locally recurrent or persistent prostate cancer who underwent salvage EBRT in our department between April 2004 and June 2008. Minimum follow-up for inclusion was 2 years. Failure with EBRT was defined as biochemical relapse (Phoenix definition) or introduction of androgen deprivation therapy (ADT). Gastrointestinal and urinary toxicity and urinary stress incontinence were scored at 12 and 24 months (Radiation Therapy Oncology Group and Ingelman Sundberg rating, respectively).
Results: The mean age of the patients was 68.8 years (range: 60-79). Mean prostate-specific antigen (PSA) before EBRT was 5.57 ng/mL (range: 2.5-14.8). Median follow-up was 36.5 ± 10.9 months (range: 24-54). No patient received adjunctive ADT. The EBRT course was well-tolerated and completed by all patients. The mean PSA nadir was 0.62 ng/mL (range: 0.03-2.4) and occurred after a median of 22 months (range: 12-36). One patient experienced biochemical failure and was prescribed ADT 30 months after EBRT. The disease-free survival rate was 83.3% at 36.5 months. There was no major EBRT-related toxicity at 12 or 24 months.
Conclusion: Our early clinical results confirm the feasibility and good tolerance of salvage radiotherapy after HIFU failure. Oncological outcomes were promising. A prospective study with longer follow-up is needed to identify factors predictive of success for salvage EBRT therapy after HIFU failure.
CUAJ has adopted an early release model, in which papers are published online in advance of their print publication. The print publication schedule remains the same: February, April, June, August, October, December; however, CUAJ is now posting new early release articles on its website (www.cuaj.ca) every other month (January, March, May, July, September, November). CUAJ early releases articles only apply to research articles.
These early release articles are peer-reviewed, accepted, edited and formatting just like print articles, except for the fact that they are released online before they are published in print and do not have a volume/issue/page number. Only the digital object identifier (DOI) is used as an identifier for the article (i.e., DOI:10.5489/cuaj.09116). The "DOI:10.5489" is the journal identifier and the "cuaj.09116" is the identifier associated with a particular article. Each CUAJ article carries a DOI, which serves as its unique electronic identification tag. As soon as an article is published in a print issue, it will be assigned a page number and transferred to that issue's table of contents on the website. The DOI remains attached to the paper to provide a persistent identifier.
For convenience, the PDF version of every early release article is given a temporary pagination, with each article beginning on page 1. This pagination, however, is unrelated to the final pagination of the print article and should not be used for citation purposes.
The CUAJ Editorial Board strongly believes that rapid online publication is a valuable service to readers and authors, and we encourage you to visit the CUAJ website often at www.cuaj.ca.